Dr. Jack Explains: CBD vs. THC

Dr. Jack D’Angelo is CITIVA’s Chief Medical Officer and renowned pain specialist. He has spent years understanding the therapeutic benefits of cannabis. Here he explains the differences between and the medical applications of CBD and THC.

Though many (if not most) of you are very familiar with the cannabinoids known as THC and CBD many are still unclear about the differences and why they matter. THC and CBD are being used more often both in the form of medical cannabis and medical cannabis products to treat a wide range of conditions yet doctors, pharmacists and regulatory bodies have a very poor understanding of them and can offer little guidance as to their use and effectiveness. Since patients must learn about this medicine on their own, let us provide a general overview.


THC or tetrahydrocannabinol is a cannabinoid found in high concentrations in cannabis plants that would be considered medicinal or recreational quality. THC is the cannabinoid that produces the psychoactive effect associated with cannabis. Patients who consume cannabis products with THC should not drive or operate heavy machinery.

When taken carefully on a standardized and consistent regimen, THC can ease a variety of symptoms without significant intoxication. Starting with doses as low as 5 mg THC can begin to alleviate pain, nausea, and insomnia.

CBD or cannabidiol is a cannabinoid found in high concentrations in cannabis plants that would be considered medicinal or hemp quality. Since cannabis that is high in CBD does not produce an intoxicating effect, it’s unnattractive for recreational consumers. Because of its medicinal qualities CBD remains in high demand among medicinal users.

CBD becomes effective effective in doses as low as 10 mg and can treat a wide range neurological and inflammatory symptoms. CBD has shown remarkable effectiveness in treating epilepsy, PTSD, anxiety, and neuropathic pain.

THC or CBD can be taken alone to great effect. (Though natural cannabis extractions will always carry at least trace amounts of the other.) However, they show a powerful synergizing effect when used in concert. Patients tend to report more symptom relief when these cannabinoids are taken together. Also, CBD appears to temper the intoxicating effects of THC so patients can enjoy its therapeutic qualities without the more pronounced psychological effects.

We hope this information is helpful to you. We aim to be a resource for people hoping to navigate the complexities of medical cannabis so if you have any questions please reach out to us on Facebook, Twitter @CITIVAllc, Instagram @citivacannameds, or email info@citiva.com.

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